5-Nitro-4-phenylpentan-2-one (1) was found to undergo hitherto unknown Me 3 SiBr/Et 3 N-promoted cyclisation into the intermediate six-membered cyclic nitronate 5. Subsequent silylation of 5 led to the corresponding 2-trimethylsilyloxy-2H-[1,2]oxazine C, which undergoes a facile [4 + 2] cyclofragmen
✦ LIBER ✦
ChemInform Abstract: Novel Me3Si-Mediated Intramolecular Cyclization/[4 + 2] Cyclofragmentation of β-Substituted γ-Nitro Ketones.
✍ Scribed by Alexander A. Tishkov; Il'ya M. Lyapkalo; Anton V. Kozincev; Sema L. Ioffe; Yuri A. Strelenko; Vladimir A. Tartakovsky
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 35 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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