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ChemInform Abstract: Novel B-Ring Modified Combretastatin Analogues: Syntheses and Antineoplastic Activity.

✍ Scribed by Toshihiro Hatanaka; Koichi Fujita; Koji Ohsumi; Ryusuke Nakagawa; Yumiko Fukuda; Yukio Nihei; Yasuyo Suga; Yukio Akiyama; Takashi Tsuji

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199911290

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Novel Combretastatin Analogues Effective Against Murine Solid Tumors: Design and Structure-Activity Relationships. -A series of combretastatin A-4 analogues, e.g. (V) and (VIII), with cis orientation of the two benzene rings and 3,4,5-trimethoxy substituents as indispensable criteria for potent cyt