Furo[2,3-d]pyrimidines and Oxazolo[5,4-d
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Andreas Martin-Kohler; JΓΆrg Widmer; Guido Bold; Thomas Meyer; Urs SΓ©quin; Peter
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Article
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2004
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John Wiley and Sons
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German
β 276 KB
π 1 views
## Abstract Receptor tyrosine kinases such as VEGFR2 (vascular endothelial growth factor receptor 2, KDR) or EGFR (epidermal growth factor receptor) play crucial roles in a variety of diseases, such as cancer. Recently, some pyrrolopyrimidines were shown to be potent EGFR inhibitors. Therefore, new