𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Nonpeptidal P2 Ligands for HIV Protease Inhibitors: Structure-Based Design, Synthesis, and Biological Evaluation.

✍ Scribed by A. K. GHOSH; J. F. KINCAID; D. E. WALTERS; Y. CHEN; N. C. CHAUDHURI; W. J. THOMPSON; C. CULBERSON; P. M. D. FITZGERALD; H. Y. LEE; S. P. MCKEE; P. M. MUNSON; T. T. DUONG; P. L. DARKE; J. A. ZUGAY; W. A. SCHLEIF; M. G. AXEL; J. LIN; J. R. HUFF


Book ID
112041063
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
27
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Structure-based drug design of nonpeptid
✍ Vincent J. Kalish; John H. Tatlock; Jay F. Davies II; Stephen W. Kaldor; Bruce A πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 290 KB

The cocrystal structures of LY289612 and LY297135 were used as a starting point in the design of nonpeptidic HIV-1 protease inhibitors. This report details the discovery of a series of novel aromatic P2 replacement groups. The 3-hydroxy-2-methyl benzoic acid group, discovered in AG1254, was incorpor

Design, Synthesis, and Biological Evalua
✍ Amos B. III Smith; et al. et al. πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.