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ChemInform Abstract: Non-covalent Complexes Between DNA-Binding Drugs and Double-Stranded Oligodeoxynucleotides: A Study by ESI Ion-Trap Mass Spectrometry.

✍ Scribed by Katty X. Wan; Toshimichi Shibue; Michael L. Gross

Publisher: John Wiley and Sons
Year: 2010
Weight: 33 KB
Volume: 31
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200014191

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The non-covalent complexes between some DNA-binding drugs and duplex oligodeoxynucleotides were studied by ionspray mass spectrometry, with the aim of evaluating the suitability of this technique to screen rapidly a series of drugs exerting their activity through non-covalent binding to speciÐc base