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ChemInform Abstract: New Weapons in the Fight Against Cancer.

✍ Scribed by I. OJIMA; P.-Y. BOUNAUD; R. J. BERNACKI

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199837280

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✦ Synopsis

New Weapons in the Fight Against Cancer. -Taxane derivatives (I) and (II) exhibit high multidrug resistance reversal activity against drug-resistant breast cancer cells when coadministered with anticancer drugs such as paclitaxel and doxorubicin. Their negligible cytotoxicity makes them attractive candidates to clinical trials.

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