ChemInform Abstract: New Synthetic Technology for the Rapid Construction of Novel Heterocycles. Part 1. The Reaction of Dess—Martin Periodinane with Anilides and Related Compounds.
✍ Scribed by K. C. Nicolaou; Yong-Li Zhong; Phil S. Baran
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Contemporary organic synthesis is faced with the challenge of developing simple methods for the rapid construction of complex, biologically relevant compounds which rival the complexity and diversity of natural products for combinatorial chemistry, biological screening, and chemical biology studies.
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## Experimental Section DMP (2.0 equiv) was added in one portion to a solution of 7 a (0.1 mmol) in benzene (4 mL) or BTF. [6] The solution was heated at reflux (or at 80 ± 85 8C for the reactions in BTF) for about 30 min at which point TLC indicated complete consumption of starting material. Dilu