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ChemInform Abstract: New Synthetic Routes for the Preparation of 2′-C-Methylene Nucleosides.

✍ Scribed by J. WOLF; C. MONNERET; R. PONTIKIS; J.-C. FLORENT

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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New Synthetic Routes for the Preparation
New Synthetic Routes for the Preparation of 2′-C-Methylene Nucleosides
✍ Junior Wolf; Claude Monneret; Renée Pontikis; Jean-Claude Florent 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 1 views

Two new routes to 2Ј,3Ј-dideoxy-2Ј-C-methylene nucleoside followed by thermal elimination of phenylsulfinic acid. The second route involved a condensation of a silylated base with analogs have been developed. The first is based upon the coupling reaction of a 1-O-acetyl 2-C-(methylphenylsulfinyl) a