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ChemInform Abstract: New Synthesis of 5,6-Dihydrothiazolo[3,2-b][1,2,4]triazoles.

✍ Scribed by E. E. Klen; F. A. Khaliullin


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


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Diarylthiazolo(3,2b) ( 1,2,4)triazoles. -Sixteen title compounds such as (I) are prepared for evaluation of potency and selectivity against human COX-1 and COX-2 enzymes. Most of the analogues in the series are very potent against the COX-2 enzyme. All of the compounds exhibit good selectivity in