ChemInform Abstract: New Synthesis of 5,6-Dihydrothiazolo[3,2-b][1,2,4]triazoles.
β Scribed by E. E. Klen; F. A. Khaliullin
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
Diarylthiazolo(3,2b) ( 1,2,4)triazoles. -Sixteen title compounds such as (I) are prepared for evaluation of potency and selectivity against human COX-1 and COX-2 enzymes. Most of the analogues in the series are very potent against the COX-2 enzyme. All of the compounds exhibit good selectivity in