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ChemInform Abstract: New Reactions of Oximinocyanoacetamides with Benzylamine: A One-Pot Entry into Isoxazole Nucleus.

✍ Scribed by Gautam Chattopadhyay; T. K. Saha; Manas Chakrabarty

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199909146

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✦ Synopsis

New Reactions of Oximinocyanoacetamides with Benzylamine: A One-Pot Entry into Isoxazole Nucleus. -Reaction of oximinocyanoacetamides (I) with benzylamine unexpectedly gives stable oximinate salts (III), which can be smoothly converted into isoxazole-3-carboxamides (V) via reaction with phenacyl bromide and subsequent cyclization. -(CHATTOPADHYAY,

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