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ChemInform Abstract: New Octahydroquinazoline Derivatives: Synthesis and Hypotensive Activity.

✍ Scribed by O. I. El-Sabbagh; Mohamed A. Shabaan; Hanan H. Kadry; Ehab Saad Al-Din

Publisher
John Wiley and Sons
Year
2011
Weight
33 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

A variety of new octahydroquinaolinone derivatives is synthesized starting with the Mannich reaction of aminocyclohexenone (I). Compounds (IXa)-(IXc) are found to possess a high hypotensive effect without causing reflex tachycardia. -(EL-SABBAGH*, O. I.; SHABAAN, M. A.

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