ChemInform Abstract: New Isoxazolidine-Based Chiral Auxiliaries for Asymmetric Syntheses.

✍ Scribed by A. ABIKO; J.-F. LIU; G. WANG; S. MASAMUNE

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199733029

✦ Synopsis

New Isoxazolidine-Based Chiral Auxiliaries for Asymmetric Syntheses.

-A series of title compounds such as (I) is prepared and tested as auxiliaries. Asymmetric alkylation and boron aldol reactions proceed with excellent selectivity with the derivatives (III) and (VI), respectively.