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ChemInform Abstract: New Efficient Synthetic Routes to Enantiomerically Pure Fluoroalkyl( arylsulfinyl)methyl Imines and Amines.

✍ Scribed by P. BRAVO; G. CAVICCHIO; M. CRUCIANELLI; A. L. MARKOVSKY; A. VOLONTERIO; M. ZANDA


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


1997

sulfoxides, sulfones, sulfenes and derivatives sulfoxides, sulfones, sulfenes and derivatives (benzene compounds) Q 0600

07 -115

New Efficient Synthetic Routes to Enantiomerically Pure Fluoroalkyl( arylsulfinyl)methyl Imines and Amines. -Two efficient routes for the preparation of enantiomerically pure fluoroalkyl(arylsulfinyl)methyl imines are reported. Hydride reduction of the imines (IIIa) and (IIIc) gives the diastereomeric sulfinylamines (VIII) and (IX) of which (IXc) is deprotected by CAN to the chiral sulfinylamine (X), a known precursor of 3,3