New anti-tumor agents. 3. Phenolic benzo
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Leonard Jurd
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Article
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1997
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Journal of Heterocyclic Chemistry
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English
β 316 KB
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## Abstract 2βAminopyridine, sesamol and 4βhydroxyβ3,5βdimethoxybenzaldehyde condense to form a Mannicb base 3b which reacts with tetronic acid to yield lactone 4c. Cyclization of 4c yields the benzopyran lactone 1b; this inhibits growth of tumors in NCI __in vitro__ tests. Alkaline hydrolysis of a