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ChemInform Abstract: New and Efficient Catalysts for Enantioselective Borohydride Reduction of Ketones and Imines

โœ Scribed by Takushi Nagata; Kiyoaki D. Sugi; Kiyotaka Yorozu; Tohru Yamada; Teruaki Mukaiyama


Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
30
Category
Article
ISSN
0931-7597

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The condensation of o-(diphenylphosphino)benzaldehyde and various chiral diamine gives a series of diimino-diphosphine tetradentate ligands, which are reduced with excess NaBH4 in refluxing ethanol to afford the corresponding diaminodiphosphine ligands in good yield. The reactivity of these ligands