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ChemInform Abstract: New Access to Methyl Formylcyclopropanecarboxylates via Diethylaminotrimethylsilane Mediated Tandem Nucleophilic Reaction of Aldehyde with Methyl 2,3-Dihalopropanoate.

✍ Scribed by Hisahiro Hagiwara; Nao Komatsubara; Takashi Hoshi; Toshio Suzuki; Masayoshi Ando


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


New Access to Methyl Formylcyclopropanecarboxylates via Diethylaminotrimethylsilane Mediated Tandem Nucleophilic Reaction of Aldehyde with Methyl 2,3-Dihalopropanoate.

-The title reaction results in formation of diastereomeric mixtures of formylcyclopropanecarboxylates. In some cases [cf. (V)/(VI)] these mixtures can be separated.