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ChemInform Abstract: Neutral Acylation (Protection) of the Indole Nitrogen: A Simple Synthesis of Indole-1-carboxylates, Indole-1-thiocarboxylates and Indole-1-carboxamides.

✍ Scribed by John E. Macor; Alison Cuff; Lyndon Cornelius

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

1999 indole derivatives, isoindole derivatives indole derivatives, isoindole derivatives R 0140

27 -136

Neutral Acylation (Protection) of the Indole Nitrogen: A Simple Synthesis of Indole-1-carboxylates, Indole-1-thiocarboxylates and Indole-1-carboxamides.

-The conversion of N-unsubstituted indoles to the title compounds is easily achieved with carbonyldiimidazole and nucleophiles under neutral reaction conditions. -(MACOR, JOHN E.; CUFF,

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