ChemInform Abstract: N-Chloro-N-sodio-2-trimethylsilyl Ethyl Carbamate: A New Nitrogen Source for the Catalytic Asymmetric Aminohydroxylation.

✍ Scribed by K. L. REDDY; K. R. DRESS; K. B. SHARPLESS

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 33 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199835128

✦ Synopsis

Asymmetric aminohydroxylation of the alkenes (I) and (IV) is performed with the title carbamate using an asymmetric catalyst. The silyl protecting group of the products is readily cleaved with fluoride under mild conditions.