ChemInform Abstract: N-Carbamoyl Analogues of Zafirlukast: Potent Receptor Antagonists of Leukotriene D4.

✍ Scribed by M. F. BROWN; A. MARFAT; ET AL. ET AL.

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199902113

✦ Synopsis

1999 indole derivatives, isoindole derivatives indole derivatives, isoindole derivatives R 0140 02 -113 N-Carbamoyl Analogues of Zafirlukast: Potent Receptor Antagonists of Leukotriene D 4 . -A series of leukotriene D 4 receptor antagonists (I) is prepared. The new compounds do not show an acceptable pharmacokinetic profile for clinical use. Further investigations on this type of derivatives are in progress. -(BROWN, M.