ChemInform Abstract: N-Acetylbornane-10,2-sultam: A Useful Enantiomerically Pure Acetate Synthon for Asymmetric Aldol Reactions.

✍ Scribed by S. BOND; P. PERLMUTTER

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199802018

✦ Synopsis

N-Acetylbornane-10,2-sultam: A Useful Enantiomerically Pure Acetate Synthon for Asymmetric Aldol Reactions. -It is demonstrated that diethylboron enolates of N-acetylbornane sultams (I) react with aldehydes with good diastereoselectivity. The opposite stereochemistry at the carbinol center is easily obtained by switching the enantiomeric series. -(BOND, S.;