ChemInform Abstract: Morita—Baylis—Hillman Reaction of Lactams and Lactones with Alkyl Halides and Epoxides Catalyzed by Hydroxysulfides.
✍ Scribed by Irene Suarez del Villar; Ana Gradillas; Gema Dominguez; Javier Perez-Castells
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 40 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
Morita—Baylis—Hillman reaction of lactam (I) and lactones (VI) with a variety of alkyl halides (II) and epoxides (IV) proceeds smoothly in the presence of a chiral hydroxy sulfide under basic conditions.
📜 SIMILAR VOLUMES
## Abstract The phosphinothiourea shown in the scheme efficiently promotes asymmetric intramolecular Morita—Baylis—Hillman reaction of aldehydes of type (I).
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