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ChemInform Abstract: Modular Synthesis of Pyrrolo[2,1-b]thiazoles and Related Monocyclic Pyrrolo Structures.

✍ Scribed by Emma E. O'Dwyer; Nessa S. Mullane; Timothy P. Smyth


Publisher
John Wiley and Sons
Year
2011
Weight
41 KB
Volume
42
Category
Article
ISSN
0931-7597

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Modular synthesis of pyrrolo[2,1-b]thiaz
✍ Emma E. O'Dwyer; Nessa S. Mullane; Timothy P. Smyth πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 318 KB

## Abstract A modular synthesis of selectively‐substituted pyrrolo[2,1‐__b__]thiazoles (Ξ”^6^ isomeric form) has been implemented, involving a distinctive bicyclization reaction of a mucobromic acid derivative followed by a Suzuki‐Miyaura coupling. A novel process of Ξ”^6^ to Ξ”^7^ isomerization of th