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ChemInform Abstract: Modification of Pseudo-C3-Symmetric Trisoxazoline and Its Application to the Friedel—Crafts Alkylation of Indoles and Pyrrole with Alkylidene Malonates.

✍ Scribed by You-Yun Zhou; Xiu-Li Sun; Ben-Hu Zhu; Jun-Cheng Zheng; Jiao-Long Zhou; Yong Tang

Publisher
John Wiley and Sons
Year
2011
Weight
36 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The new pseudo‐C~3~‐symmetric hetero‐trisoxazolines are prepared on a gram scale and in combination with copper triflate applied to the asymmetric Friedel—Crafts alkylation of both indoles (II) and pyrrole (V) with alkylidene malonates (I) and (IV), respectively.

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