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ChemInform Abstract: Mixed Opioidic Agonists/Antagonists and Partial Agonists

✍ Scribed by Thomas Christoph; Helmut Buschmann

Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
33
Category
Article
ISSN
0931-7597

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The TIPP opioid peptide family: Developm
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✍ Peter W. Schiller; Grazyna Weltrowska; Irena Berezowska; Thi M.-D. Nguyen; Brian πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 135 KB

The discovery of the prototype ␦ opioid antagonists TIPP (H-Tyr-Tic-Phe-Phe-OH) and TIP (H-Tyr-Tic-Phe-OH) in 1992 was followed by extensive structure-activity relationship studies, leading to the development of analogues that are of interest as pharmacological tools or as potential therapeutic agen