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ChemInform Abstract: Metalation of Arylmethyl Alkyl Ethers.

โœ Scribed by U. AZZENA; L. PILO; A. SECHI


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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Unexpected Aldol Condensations under Williamson Arylmethyl Ether Synthesis Conditions. -O-Methylation of 5-bromosalicylaldehyde (Ia) under standard conditions using dimethyl sulfate in refluxing acetone for 2h gives the expected methyl ether (Va) in high yield. However, prolonged reflux leads to th