The TMSOTf mediated nucleophilic cleavage of a-aminoacetals can be used to prepare a variety of substituted amines, with variable levels of stereocontrol depending on the substitution patterns. The reaction most likely proceeds via either an a-alkoxy aziridinium ion or an a-oxocarbenium ion dependin
✦ LIBER ✦
ChemInform Abstract: Mechanistic and Stereochemical Aspects of the Lewis Acid Mediated Cleavage of α-Aminoacetals.
✍ Scribed by Mark A. Graham; Alan H. Wadsworth; Mark Thornton-Pett; Benedetta Carrozzini; Giovanni L. Cascarano; Christopher M. Rayner
- Book ID
- 101918481
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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