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ChemInform Abstract: Mapping the Mechanism of Nickel-Ferrophite Catalyzed Methylation of Baylis—Hillman-Derived SN2′ Electrophiles.

✍ Scribed by Andrew Novak; Maria Jose Calhorda; Paulo Jorge Costa; Simon Woodward


Publisher
John Wiley and Sons
Year
2009
Weight
43 KB
Volume
40
Category
Article
ISSN
0931-7597

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Mapping the Mechanism of Nickel-Ferrophi
✍ Andrew Novak; Maria José Calhorda; Paulo Jorge Costa; Simon Woodward 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 390 KB

## Abstract Enantioselective Ni‐catalysed methylation of Baylis–Hillman‐derived allylic electrophiles in the presence of ferrophite ligands has been investigated computationally and experimentally. The sense and degree of enantioselectivity attained is independent of both the leaving group and the