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ChemInform Abstract: Macrocyclic Polyamine Lactam Synthesis by Diphenyl Ether Closure of 23-, 24- and 28-Membered Rings.

✍ Scribed by S. CARRINGTON; A. H. FAIRLAMB; I. S. BLAGBROUGH


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Macrocyclic Polyamine Lactam Synthesis by Diphenyl Ether Closure of 23-, 24-and 28-Membered Rings.

-The first synthesis of 23-, 24-, and 28-membered ring polyamine lactam conjugates (IV), (VII), and (VIII), which are nitro-substituted analogues of cadabicine class alkaloids, proceeds via the procedures described in the scheme. -(CARRINGTON, S.; FAIRLAMB,