ChemInform Abstract: Ligand Recognition in the Opioid Receptors by Modeling Methods and the Design of Opioids

The Design and Synthesis of a Novel Quin

The Design and Synthesis of a Novel Quinolizidine Template for Potent Opioid and Opioid Receptor-Like (ORL1, NOP) Receptor Ligands.

✍ Ling Jong; Nurulain Zaveri; Lawrence Toll 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 120 KB 👁 1 views

## Abstract For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract: Affinity Labels as

ChemInform Abstract: Affinity Labels as Tools for the Identification of Opioid Receptor Recognition Sites

✍ Philip S. Portoghese; Rachid El Kouhen; Ping Y. Law; Horace H. Loh; Bertrand Le 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Theoretical studies on opioid receptors

Theoretical studies on opioid receptors and ligands. I. Molecular modeling and QSAR studies on the interaction mechanism of fentanyl analogs binding to μ-opioid receptor

✍ Hua Liang Jiang; Xiao Qin Huang; Suo Bao Rong; Xiao Min Luo; Jian Zhong Chen; Yu 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 2 views

Based on our previous result of the three-dimensional model of the µ-opioid receptor, binding conformations of 13 fentanyl analogs and three-dimensional structures for the complexs of these analogs with µ-opioid receptor were constructed employing the molecular modeling method and our binding confor

ChemInform Abstract: Novel Delta-Opioid-

ChemInform Abstract: Novel Delta-Opioid-Receptor-Selective Ligands in the 14-Alkoxy-Substituted Indolo- and Benzofuromorphinan Series.

✍ Dauren Biyashev; Krisztina Monory; Sandor Benyhe; Johannes Schuetz; Martin Koch; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Opioid peptide receptor studies, 11: Inv

Opioid peptide receptor studies, 11: Involvement of Tyr148, Trp318 and His319 of the rat μ-opioid receptor in binding of μ-selective ligands

✍ Heng Xu; Yi-Feng Lu; John S. Partilla; Qiao-Xi Zheng; Jia-Bei Wang; George A. Br 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 1 views

Previous data obtained with the cloned rat µ opioid receptor demonstrated that the ''super-potent'' opiates, ohmefentanyl (RTI-4614-4) and its four enantiomers, differ in binding affinity, potency, efficacy, and intrinsic efficacy. Molecular modeling (Tang et al., 1996) of fentanyl derivatives bindi

ChemInform Abstract: Design, Synthesis,

ChemInform Abstract: Design, Synthesis, and Biological Evaluation of 3-Amino-3-phenylpropionamide Derivatives as Novel μ Opioid Receptor Ligands.

✍ Martin P. Allen; James F. Blake; Dianne K. Bryce; Mary E. Haggan; Spiros Liras; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views