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ChemInform Abstract: Lewis Acid Catalyzed Highly Stereoselective Domino-Ring-Opening Cyclization of Activated Aziridines with Enolates: Synthesis of Functionalized Chiral γ-Lactams.

✍ Scribed by Manas K. Ghorai; Deo Prakash Tiwari


Publisher
John Wiley and Sons
Year
2010
Weight
51 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

Starting from alkyl‐substituted aziridines such as (VI) only moderate diastereoselectivity is achieved.