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ChemInform Abstract: Iron-Catalyzed Synthesis of Polysubstituted Pyrroles via [4C + 1N] Cyclization of 4-Acetylenic Ketones with Primary Amines.

✍ Scribed by Yeming Wang; Xihe Bi; Dehua Li; Peiqiu Liao; Yidong Wang; Jin Yang; Qian Zhang; Qun Liu

Book ID: 102058841
Publisher: John Wiley and Sons
Year: 2011
Weight: 43 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201119110

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✦ Synopsis

Abstract

A convenient procedure is elaborated for the synthesis of tetra‐ and pentasubstituted pyrroles (III) using an iron‐catalyzed cyclization of acetylenic ketones (I) with amines (II) (31 examples).

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