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ChemInform Abstract: Iron-Catalyzed Synthesis of Functionalized 2H-Chromenes via Intramolecular Alkyne—Carbonyl Metathesis

✍ Scribed by Krishnendu Bera; Soumen Sarkar; Srijit Biswas; Sukhendu Maiti; Umasish Jana


Publisher
John Wiley and Sons
Year
2011
Weight
38 KB
Volume
42
Category
Article
ISSN
0931-7597

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Palladium-Catalyzed Intramolecular Alkyne-α,β-Unsaturated Carbonyl Coupling. A Formal Synthesis of (+)-Pilocarpine. -Pd-catalyzed enyne coupling of (E) or (Z) alkynoates (I) or (III) provides the alkenyl substituted lactones (II) highly stereoselectively. After esterification with (+)-dimethyltart