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ChemInform Abstract: Iridium-Catalyzed Enantioselective Hydrogenation of Imines in Supercritical Carbon Dioxide.

✍ Scribed by Sabine Kainz; Axel Brinkmann; Walter Leitner; Andreas Pfaltz


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Iridium-Catalyzed Enantioselective Hydrogenation of Imines in Supercritical Carbon Dioxide.

-Supercritical CO 2 is used as an environmentally benign alternative solvent for the enantioselective hydrogenation of prochiral imines. Main advantages of this reaction medium are the low catalyst loading, efficient product isolation and catalyst recycling. The substrate is found to be of key importance for solubilizing the catalytically active species. Good levels of asymmetric induction are observed only with catalysts containing


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