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ChemInform Abstract: Intrinsic and Intramolecular Lipophilicity Effects in O-Glucuronides.

โœ Scribed by Y. GIROUD; P.-A. CARRUPT; A. PAGLIARA; B. TESTA; R. G. DICKINSON

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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Intrinsic and Intramolecular Lipophilici
Intrinsic and Intramolecular Lipophilicity Effects in O-Glucuronides
โœ Yvan Giroud; Pierre-Alain Carrupt; Alessandra Pagliara; Bernard Testa; Ronald G. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 773 KB

In this study, we compared the lipophilicity of 0-glucuronides and their aglycones. Distribution coefficients (log D ) and P values of neutral species (log P ) were determined by centrifugal partition chromatography (CPC) in octanol/buffer systems. Two-phase potentiometry was also used to measure th