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ChemInform Abstract: Intramolecular vs. Intermolecular Induction in the Diastereoselective Catalytic Reduction of Enantiomerically Pure Ketones with Borane in the Presence of Cyclic β-Amino Alcohols.

✍ Scribed by I. REINERS; J. WILKEN; J. MARTENS


Book ID
112030775
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
27
Category
Article
ISSN
0931-7597

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Intramolecular vs. intermolecular induct
✍ I. Reiners; J. Wilken; J. Martens 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 433 KB

Asymmetric reduction of various enantiomerically pure ketones was carded out by using oxazaborolidine catalysts with a variety of achiral and chiral ligands. The efficiency of chiral 1,2-amino alcohols as well as the effect of the stereogenic centers in the substrate on the catalytic asymmetric redu