The reaction of hydroxy alkenes 5, 7, and 8 with CO and MeOH in the presence of PdCI 2 and CuCI 2 gave tetrahydropyrans 9, 11, and 12, respectively. Yields were dependent upon the configuration of substituents in the hydroxy alkene; in all cases, the tetrahydropyran was produced with 2,6-cis configu
β¦ LIBER β¦
ChemInform Abstract: Intramolecular Palladium-Catalyzed Alkoxy Carbonylation of 6-Hydroxy-1-octenes. Stereoselective Synthesis of Substituted Tetrahydropyrans.
β Scribed by James D. White; Jian Hong; Lonnie A. Robarge
- Book ID
- 101880426
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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