ChemInform Abstract: Intramolecular Cyclization of N-Hetarylphosphinimidic Isocyanates in the Synthesis of 1,7-Dihydro-4H-imidazo[4,5-d][1,3,2]diazaphosphinin-4-one (2-Phosphapurine).

✍ Scribed by Anatoliy P. Marchenko; Georgiy K. Koydan; Anastasia S. Huryeva; Radomyr V. Smaliy; Aleksandr A. Yurchenko; Anatoliy N. Alekseenko

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 27 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201110180

✦ Synopsis

Intramolecular Cyclization of N-Hetarylphosphinimidic Isocyanates in the Synthesis of 1,7-Dihydro-4H-imidazo[4,5-d][1,3,2]diazaphosphinin-4-one (2-Phosphapurine). -The synthesis of previously unknown target compounds (V) and (VII) containing an endocyclic P=N double bond is reported. This novel approach may be useful for the preparation of related phosphorus-containing fused heterocycles. On long standing in open air, (VII) is quantitatively converted to the disulfide (VIII). -(MARCHENKO, A.