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ChemInform Abstract: Insulin Semisynthesis

โœ Scribed by J. Gwynfor Davies; Carmichael J. A. Wallace


Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
31
Category
Article
ISSN
0931-7597

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Enzymatic semisynthesis of human insulin
โœ Kazuyuki Morihara ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 482 KB

## Abstract Peptide bond formation can be enzymatically catalysed by the reverse reaction of proteases. Application is seen in the industrial production of human insulin. Human insulin derivative can be enzymatically prepared using either porcine insulin or the single chain B(1โ€“29)โ€A(1โ€“21) insulin