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ChemInform Abstract: Improved Procedure for Preparing 2,2-Dimethyl-4,6-dioxo-1,3-dioxane ( Meldrum′s Acid).

✍ Scribed by I. N. NESTEROVA; A. K. SHANAZAROV; A. M. POZNYAK; M. I. LAKOZA; B. V. SHEMERYANKIN; V. G. GRANIK


Book ID
112021608
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
26
Category
Article
ISSN
0931-7597

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Simple preparation of epimeric 2,6-dimet
✍ Juraj Bernát; Ladislav Kniežo; Gabriela Birošová; Ján Imrich; Jaroslav Podlaha; 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 647 KB

One-pot reaction of acetaldehyde, KSCN and POCl3 affords 2,6dimethyl-4-isothiocyanato-1,3dioxane 4 in good yield. Compound 4 reacts with primary amines to give crystalline re/-2S,4R,6S-2,6dimethyl-4-(N'substituted thiourefdo)-1,3dioxanes 5. The obtained thioureas 5 with axial thioureido group are sp