ChemInform Abstract: Highly Substituted 2,3-Dihydroisoxazoles by Et3N-Catalyzed Tandem Reaction of Electron-Deficient 1,3-Conjugated Enynes with Hydroxylamines.
✍ Scribed by Xiuzhao Yu; Bo Du; Kai Wang; Junliang Zhang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
A wide range of multifunctionalized 2,3‐dihydroisoxazoles is prepared, tolerating many functional groups as ketones, esters, aldehydes, aromatic and aliphatic substituents.
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## Abstract Phase‐transfer‐catalyzed nucleophilic addition—cyclization of electron‐deficient 1,3‐conjugated enynes towards 1,3‐dicarbonyl compounds provides access to a wide range of 4H‐pyrans such as (III) and (V).
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