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ChemInform Abstract: Highly Organocatalytic Asymmetric Michael—Ketone Aldol—Dehydration Domino Reaction: Straightforward Approach to Construct Six-Membered Spirocyclic Oxindoles.

✍ Scribed by Liang-Liang Wang; Lin Peng; Jian-Fei Bai; Qing-Chun Huang; Xiao-Ying Xu; Li-Xin Wang


Publisher
John Wiley and Sons
Year
2011
Weight
29 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The title reaction affords six‐membered spirocyclic oxindoles (III), bearing contiguous stereogenic centers in high yields and excellent dia‐ and enantioselectivities.