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ChemInform Abstract: Highly Endo- and Enantioselective Asymmetric Nitrone Cycloadditions Catalyzed by the Aqua Complex of 4,6-Dibenzofurandiyl-2,2′-bis(4-phenyloxazoline)—Nickel(II) Perchlorate. Transition Structure Based on Dramatic Effect of MS 4A on Selectivities.

✍ Scribed by Shuji Kanemasa; Yoji Oderaotoshi; Junji Tanaka; Eiji Wada


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Highly Endo-and Enantioselective Asymmetric Nitrone Cycloadditions Catalyzed by the Aqua Complex of 4,6-Dibenzofurandiyl-2,2'bis(4-phenyloxazoline)-Nickel(II) Perchlorate. Transition Structure Based on Dramatic Effect of MS 4A on Selectivities.

-The aqua complex derived from the chiral ligand and Ni(ClO 4 ) 2 •6H 2 O acts as excellent chiral Lewis acid catalyst. The presence of mol. sieves 4A in the title reaction is essential to obtain the high enantioselectivities up to ¿99%. -(KANEMASA,