## Abstract An enantioselective Michael addition of ethyl 4,4,4‐trifluoro‐3‐oxobutanoate to __α__,__β__‐unsaturated ketone esters using a chiral alkyl‐substituted thiourea catalyst is reported. Excellent levels of stereo‐induction (up to 98% __ee__) under mild reaction conditions were obtained to a
✦ LIBER ✦
ChemInform Abstract: Highly Enantioselective Synthesis of α-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-Substituted Thiourea Catalyst Derived from Amino Acid.
✍ Scribed by Peng Li; Gang Zhao; Shizheng Zhu
- Book ID
- 112043152
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 37 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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