ChemInform Abstract: Highly Enantioselective Palladium-Catalyzed Umpolung Allylation of Aldehydes.

✍ Scribed by Shou-Fei Zhu; Xiang-Chen Qiao; Yong-Zhen Zhang; Li-Xin Wang; Qi-Lin Zhou

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 42 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201137032

✦ Synopsis

Abstract

By using a sterically hindered chiral monodentate spiro phosphite ligand, aromatic or aliphatic aldehydes undergo the title reaction with allylic alcohols as well as allylic donors.