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ChemInform Abstract: Highly Efficient Preparation of Optically Active 5-Hydroxy-3-oxoesters by Enantioselective Reaction of Diketene with Aldehydes Promoted by Novel Chiral Schiff Base-Titanium Alkoxide Complexes.

โœ Scribed by M. HAYASHI; K. TANAKA; N. OGUNI


Book ID
112024614
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
27
Category
Article
ISSN
0931-7597

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โœ Masahiko Hayashi; Kiyoshi Tanaka; Nobuki Oguni ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 199 KB

Optically active 5-hydroxy-3-oxoesters 1 can be obtained in up to 91% enantiomeric excess (e.e.) by the enantioselective reaction of diketene with aldehydes promoted by novel chiral Schiff base,---titanium alkoxide complexes. Optically active derivatives 1 can be converted into 6-substituted 4-hydr