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ChemInform Abstract: Highly Efficient and Practical Syntheses of Lavendamycin Methyl Ester and Related Novel Quinolindiones.

✍ Scribed by M. BEHFOROUZ; J. HADDAD; W. CAI; M. B. ARNOLD; F. MOHAMMADI; A. C. SOUSA; M. A. HORN

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199706226

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✦ Synopsis

Highly Efficient and Practical Syntheses of Lavendamycin Methyl Ester and Related Novel Quinolindiones.

-An efficient method for the preparation of multigram amounts of the potent antitumor agent lavendamycin methyl ester (VI) is reported. The procedure is based on a novel route to the dione intermediate (V).

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