ChemInform Abstract: Highly Efficient Alkylation of Epoxides with R3Al/H2O Systems Based on the Double Activation of Epoxy Oxygens.

✍ Scribed by Noriko Abe; Hideo Hanawa; Keiji Maruoka; Minoru Sasaki; Masaaki Miyashita

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 34 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199941055

✦ Synopsis

Highly Efficient Alkylation of Epoxides with R 3 Al/H 2 O Systems Based on the Double Activation of Epoxy Oxygens.

-Trialkylaluminum reagents [cf (II)] modified with substoichiometric amounts of water are found to be superior for the alkylative ring opening of epoxides such as (I) and (VI). Bidentate bis(dialkyl)aluminoxanes such as (IX) seem to be the active species for the double activation of the epoxides. -(ABE, NORIKO;