𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Highly Diastereoselective Synthesis of Quaternary α-Trifluoromethyl α-Amino Acids by Addition of Benzylzinc Reagents to Chiral Imines of Trifluoropyruvate.

✍ Scribed by Jie Yang; Qiao-Qiao Min; Yi He; Xingang Zhang

Publisher
John Wiley and Sons
Year
2011
Weight
43 KB
Volume
42
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The title process renders possible a highly diastereoselective synthesis (<90% d.e.) of amino acid esters (III) and (V).

📜 SIMILAR VOLUMES

ChemInform Abstract: Highly Diastereosel
ChemInform Abstract: Highly Diastereoselective Synthesis of Quaternary α-Trifluoromethyl α-Amino Acids from Chiral Imines of Trifluoropyruvate.
✍ Qiao-Qiao Min; Chun-Yang He; Haibing Zhou; Xingang Zhang 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 34 KB

## Abstract An efficient highly diastereoselective synthesis of quaternary α‐trifluoromethyl amino acids (III) and (V) is developed via allylation of enantiopure imines of trifluoropyruvate (I).