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ChemInform Abstract: Highly Diastereoselective ortho-Lithiation of 1,1′-Bis(oxazolinyl) ferrocene Directed to C2-Symmetric Chiral Ligands.

✍ Scribed by W. ZHANG; Y. ADACHI; T. HIRAO; I. IKEDA


Book ID
112033369
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
27
Category
Article
ISSN
0931-7597

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Highly diastereoselective ortho-lithiati
✍ Wanbin Zhang; Yoichi Adachi; Toshikazu Hirao; Isao Ikeda 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 572 KB

C2-Symmetric 1, l',2,2'-tetrasubstituted ferrocene derivatives are prepared in high yields from chiral 1,1'-bis(oxazolinyl)ferrocenes v/a diastereoselective o,o'-dilithiation with sec-butyUithium followed by nucleophilic substitution. 1, l'-Bis(oxazolinyl)ferrocenes were prepared from 1,1 '-ferrocen