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ChemInform Abstract: From Sugar Lactones to Stereodefined γ-Alkylidenebutenolides — Synthesis of Analogues of the γ-Alkylidenebutenolide Antibiotics Lissoclinolide and Tetrenolin.

✍ Scribed by F. C. GOERTH; A. UMLAND; R. BRUECKNER

Publisher: John Wiley and Sons
Year: 2010
Weight: 40 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199839098

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✦ Synopsis

From Sugar Lactones to Stereodefined γ-Alkylidenebutenolides -Synthesis of Analogues of the γ-Alkylidenebutenolide Antibiotics Lissoclinolide and Tetrenolin.

-Analogues of the antibiotics tetrenolin (XI) and lissoclinolide (XII) are prepared in order to study the influence of the configuration of the C=Cγ bond on the bioactivity of γ-alkylidenebutenolides.

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